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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED1
All Species:
30
Human Site:
S1543
Identified Species:
60
UniProt:
Q15648
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15648
NP_004765.2
1581
168478
S1543
S
P
I
S
S
D
Q
S
L
S
M
T
S
N
T
Chimpanzee
Pan troglodytes
XP_001172395
1581
168474
T1543
S
P
I
S
S
D
Q
T
L
S
M
T
S
N
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537654
1583
168625
S1545
S
P
I
S
S
D
Q
S
L
S
M
T
S
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q925J9
1575
167122
T1537
S
P
I
S
S
D
P
T
A
S
V
T
N
N
P
Rat
Rattus norvegicus
NP_001127833
1567
166392
T1529
S
P
I
S
S
D
Q
T
S
S
M
T
N
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521297
422
46589
F397
D
S
P
G
I
L
Q
F
E
V
C
P
L
S
D
Chicken
Gallus gallus
XP_418125
1594
169410
S1556
S
P
I
S
A
D
Q
S
L
S
M
A
S
S
A
Frog
Xenopus laevis
Q6INP8
1570
165663
T1535
S
P
I
S
A
D
P
T
M
A
M
S
G
G
S
Zebra Danio
Brachydanio rerio
XP_700209
1694
176982
S1657
S
P
I
S
S
E
T
S
V
S
L
L
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP05
1475
149513
L1450
Q
S
G
N
E
G
L
L
N
L
S
S
T
A
G
Honey Bee
Apis mellifera
XP_395879
1811
193227
S1767
P
P
P
A
F
P
A
S
P
S
V
S
V
H
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786427
2421
258175
M2089
S
D
N
G
S
S
K
M
P
S
M
S
S
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98
N.A.
94.4
93.9
N.A.
24.4
87.6
72.5
56.4
N.A.
22
24.4
N.A.
25.7
Protein Similarity:
100
100
N.A.
98.9
N.A.
97.1
96.5
N.A.
25.7
93.5
81.7
69
N.A.
38.9
41.1
N.A.
38.5
P-Site Identity:
100
93.3
N.A.
100
N.A.
60
73.3
N.A.
6.6
73.3
40
53.3
N.A.
0
20
N.A.
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
80
86.6
N.A.
13.3
86.6
80
80
N.A.
20
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
17
0
9
0
9
9
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
0
0
0
59
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
17
0
9
0
0
0
0
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
67
0
9
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
9
% K
% Leu:
0
0
0
0
0
9
9
9
34
9
9
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
9
9
0
59
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
9
0
0
0
17
42
0
% N
% Pro:
9
75
17
0
0
9
17
0
17
0
0
9
0
0
17
% P
% Gln:
9
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
75
17
0
67
59
9
0
42
9
75
9
34
50
25
9
% S
% Thr:
0
0
0
0
0
0
9
34
0
0
0
42
9
0
25
% T
% Val:
0
0
0
0
0
0
0
0
9
9
17
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _